Last checked September 2026 against 19 sources · Editorial policy
Happy Mammoth Hormone Harmony review: what is in it and does it work
Hormone Harmony is a Happy Mammoth supplement sold for menopause symptoms, mood and bloating. Its current product page lists 10 plant extracts, including KSM-66 ashwagandha, chaste tree, maca, wild yam and fennel, and the label groups them into blends without individual doses. Hormone Harmony itself has no published trials. Of its ingredients, ashwagandha, fennel and maca have small menopause trials.
Hormone Harmony blends 10 herbs for menopause. What the label lists, which ingredients have trials, how the formula changed since 2023, and who should skip it.
Hormone Harmony for menopause: expectation vs reality
What people often expect
“Hormone Harmony balances hormones naturally, and 2.4 million women prove it works”
What the evidence shows
The 2.4 million figure is the company's own customer count, not a trial. No study has tested Hormone Harmony. Its label hides the doses inside 3 blends, so you can't compare them with the doses used in research. Wild yam, one of its headline herbs, did no better than placebo in a 2001 trial and didn't change progesterone levels.
Hormone Harmony review: ingredients, evidence and safety
What's in Hormone Harmony now
The product page lists 10 extracts: KSM-66 ashwagandha, broccoli, chamomile, chaste tree berry, fennel seed, gymnema, Peruvian maca, rhodiola, rosemary and wild yam. The December 2023 label in the NIH database groups the herbs into three blends of 810 mg, 775 mg and 450 mg, with no dose for each herb. The daily serving is 3 capsules, so a jar of 72 lasts 24 days, not a full month.
How the Hormone Harmony formula changed
A March 2023 label still listed each dose: fennel 500 mg, maca 300 mg, chamomile 220 mg, broccoli sprout 200 mg, berberine 150 mg, chaste tree 150 mg, American ginseng 150 mg, gymnema 100 mg, ashwagandha 100 mg, rhodiola 80 mg, wild yam 60 mg and rosemary 25 mg. Berberine and American ginseng no longer appear on the current product page. Check the label on the jar you actually receive.
Ashwagandha: the strongest ingredient evidence
In a 2021 trial, 100 women in perimenopause took 300 mg of ashwagandha root extract twice a day or placebo for 8 weeks, and 91 finished. Menopause symptom scores, quality of life and hot flash scores improved more than on placebo. The 2023 Hormone Harmony label listed 100 mg of ashwagandha a day, far below the trial dose, and current doses aren't disclosed.
Learn more →Fennel and maca: small trials
In a 2017 trial of 90 postmenopausal women, 100 mg fennel capsules twice a day for 8 weeks improved menopause symptom scores more than placebo. A 2011 systematic review found 4 small trials of maca, all favorable, but called the evidence limited and said its safety hadn't been proven. Hormone Harmony doesn't disclose its fennel or maca doses.
Learn more →Wild yam and chaste tree: the hormone herbs
Wild yam is often sold as a natural progesterone, but in a 2001 trial of 23 women, wild yam extract didn't change progesterone levels and didn't beat placebo for symptoms. Chaste tree (vitex) is studied mainly for premenstrual symptoms. NCCIH says it may not be safe for women with hormone-sensitive conditions such as breast, uterine or ovarian cancer.
Learn more →Rhodiola, chamomile, gymnema, broccoli and rosemary
The other five extracts are marketed for mood, sleep, cravings and estrogen balance. We found no clinical trials of any of them for menopause symptoms. They aren't harmless by default: herbs can interact with medicines, and with the doses hidden inside blends, neither you nor your doctor can tell how much of each you're taking.
Hormone Harmony side effects and who should skip it
The label lists no specific side effects. Two ingredients carry known cautions. NCCIH says ashwagandha has rarely been linked to liver injury, shouldn't be used in pregnancy, and isn't recommended before surgery or with autoimmune or thyroid disorders. Chaste tree may not be safe with hormone-sensitive cancers. No trial has tested Hormone Harmony together with hormone therapy, so ask your prescriber before combining them.
Price and the 60-day guarantee
Happy Mammoth sells Hormone Harmony mainly on its own site, where prices depend on your country and the number of jars, with a subscribe-and-save option. Its 60-day money-back guarantee covers the first bottle only. Because a jar lasts 24 days, two jars fit inside the guarantee window, so judge it by then.
What guidelines say about menopause supplements
The Menopause Society's 2023 position statement doesn't recommend herbal supplements for hot flashes, because trials haven't shown they work better than placebo. Supplements also don't need FDA approval before they're sold. For hot flashes, hormone therapy and prescription non-hormonal drugs have far stronger evidence, and they work within weeks rather than leaving you guessing.
Learn more →Hormone Harmony by the numbers
0
3
300 mg
2.4 million
Trial results come from studies of single herbs, not of Hormone Harmony.
We may earn a commission if you buy through links on this page. It doesn't change what we recommend. How this works →
Hormone Harmony vs options with better evidence
Hormone Harmony
Good for
One product aimed at mood, sleep, bloating and hot flashes; 60-day guarantee on the first bottle.Watch
No trials; doses hidden in blends; formula changed since 2023.Ashwagandha on its own
Learn more →Good for
The one ingredient with a perimenopause trial, at a known dose of 300 mg twice a day.Watch
Rare liver injury; avoid with thyroid or autoimmune disease and in pregnancy.Amberen Perimenopause
Learn more →Good for
Hormone-free; tested in a 90-day placebo-controlled trial in perimenopause.Watch
Check price on Amazon →
Company-linked research only.Estroven Complete
Learn more →Good for
Hormone-free rhubarb extract; a randomized trial showed fewer hot flashes.Watch
Check price on Amazon →
Evidence mainly from one research group.Prescription non-hormonal treatment
Learn more →Good for
Recommended by The Menopause Society for hot flashes, with large trials.Watch
Needs a prescription.
Before you buy Hormone Harmony
- Read the label on the jar against this page: berberine and American ginseng were in the formula in 2023 but aren't on the product page now.
- Skip it if you have a thyroid or autoimmune disorder, are pregnant or breastfeeding, or have surgery coming up: it contains ashwagandha.
- Avoid it after breast, uterine or ovarian cancer: it contains chaste tree.
- Use the 60-day guarantee: note the start date and decide before day 60.
- Show the full ingredient list to your pharmacist if you take any regular medicine.
When to stop Hormone Harmony and see a doctor
Urgent: Yellow skin or eyes, dark urine, itching or new tiredness on Hormone Harmony
Stop it and get liver blood tests; ashwagandha has rarely been linked to liver injury.
Urgent: Low mood that lasts more than two weeks, or thoughts of self-harm
See a doctor rather than relying on a supplement. In a crisis, call or text 988.
More →Any bleeding after menopause
See a doctor; bleeding always needs checking, whatever you're taking.
More →Hot flashes or night sweats that wreck your sleep
Ask about prescription treatment; it works far better than herbal blends.
More →
Happy Mammoth Hormone Harmony: questions women ask
Does Hormone Harmony work?
Nobody knows, because Hormone Harmony hasn't been tested in a published trial. A few of its herbs, such as ashwagandha and fennel, helped in small menopause trials, but at doses you can't check against the blends on the label. Customer reviews can't separate the product's effect from placebo and time.
Is Hormone Harmony safe?
Most women can take its herbs short term without serious problems, but two ingredients carry cautions. Ashwagandha has rarely been linked to liver injury and isn't advised with thyroid or autoimmune disorders or in pregnancy. Chaste tree may not be safe after hormone-sensitive cancers.
What are the ingredients in Hormone Harmony?
The current product page lists KSM-66 ashwagandha, broccoli, chamomile, chaste tree berry, fennel seed, gymnema, Peruvian maca, rhodiola, rosemary and wild yam. Earlier labels from 2023 also included berberine and American ginseng. Doses for each herb aren't disclosed on the newer label.
What are the side effects of Hormone Harmony?
The label doesn't list specific side effects. Watch for signs of liver problems, such as yellow skin or eyes and dark urine, which have rarely been linked to ashwagandha. Tell your doctor about it before surgery and if you take thyroid medicine.
How long does Hormone Harmony take to work?
There's no trial to say. The herb trials it borrows from ran for 8 weeks, and the brand's guarantee lasts 60 days on the first bottle. If you see no change in sleep, mood or hot flashes by then, it's unlikely to help.
Is Happy Mammoth legit?
It's a real company selling real supplements with a money-back guarantee on the first bottle. But its claims to balance hormones and relieve menopause symptoms rest on single-herb studies, not trials of its products, and the 2.4 million figure is its own customer count.
Can I take Hormone Harmony with HRT?
It hasn't been studied with hormone therapy. Chaste tree and wild yam are sold as hormone-balancing herbs, so check with your prescriber first. If HRT controls your symptoms, there's little reason to add a herbal blend on top.
Related →Does Hormone Harmony help with weight loss?
There's no evidence it does. The weight-related herbs, such as gymnema and the berberine in older formulas, haven't been tested for menopause weight in this product. Strength training, protein and sleep have better evidence for midlife weight.
Related →Hormone Harmony vs Provitalize: which is better?
Neither has been tested in a published trial. Hormone Harmony is a herbal blend aimed at mood and hormones; Provitalize is a probiotic and turmeric blend aimed at weight and bloating, with a liver safety question of its own. Compare both reviews before you buy either.
Related →Sources
- Happy Mammoth. Hormone Harmony product page. Accessed October 2026.
- NIH Office of Dietary Supplements. Dietary Supplement Label Database: Happy Mammoth Hormone Harmony label, entered December 2023.
- Gopal S, Ajgaonkar A, Kanchi P, et al. Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study. J Obstet Gynaecol Res. 2021;47(12):4414-4425.
- Rahimikian F, Rahimi R, Golzareh P, et al. Effect of Foeniculum vulgare Mill. (fennel) on menopausal symptoms in postmenopausal women: a randomized, triple-blind, placebo-controlled trial. Menopause. 2017;24(9):1017-1021.
- Lee MS, Shin BC, Yang EJ, et al. Maca (Lepidium meyenii) for treatment of menopausal symptoms: A systematic review. Maturitas. 2011;70(3):227-33.
- Komesaroff PA, Black CV, Cable V, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001;4(2):144-50.
- NIH Office of Dietary Supplements. Dietary Supplement Label Database: Happy Mammoth Hormone Harmony label, entered March 2023.
- NCCIH. Chasteberry: usefulness and safety.
- National Center for Complementary and Integrative Health. Turmeric: usefulness and safety.
- NCCIH. Ashwagandha: usefulness and safety.
- The North American Menopause Society. The 2023 nonhormone therapy position statement of The North American Menopause Society. Menopause. 2023;30(6):573-590.
- US Food and Drug Administration. Dietary supplements.
- Federal Communications Commission. 988 Suicide & Crisis Lifeline.
- NHS. Postmenopausal bleeding.
- Kachko VA, Shulman LP, Kuznetsova IV, et al. Clinical Evaluation of Effectiveness and Safety of Combined Use of Dietary Supplements Amberen(®) and Smart B(®) in Women with Climacteric Syndrome in Perimenopause. Adv Ther. 2024;41(8):3183-3195.
- Amberen. Perimenopause capsules product page (checked September 2026).
- Heger M, Ventskovskiy BM, Borzenko I, et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. Menopause. 2006;13(5):744-59.
- Greendale GA, Sternfeld B, Huang M, et al. Changes in body composition and weight during the menopause transition. JCI Insight. 2019;4(5):e124865.
- NIH Office of Dietary Supplements. Dietary Supplement Label Database: Better Body Co. Provitalize label, entered 2024.
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