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Night sweats: causes in women and when to worry
Night sweats are sweating heavy enough to soak your nightclothes and bedding even though the room is cool. The most common causes are menopause, anxiety, medicines such as some antidepressants, steroids and painkillers, low blood sugar, and alcohol or drugs. In women in perimenopause, hot flashes during sleep are the usual reason. Sweats with a fever, cough or weight loss need a doctor.
Perimenopause is a common cause in women in their 40s, but medications, infections, thyroid problems and anxiety cause night sweats too. Red flags to check.
Night sweats: what people fear vs what research shows
What people often expect
“Night sweats mean something serious is wrong”
What the evidence shows
A systematic review of the research found night sweats are common and nonspecific: reported by 10% of older primary care patients and up to 60% of women on an obstetrics ward. Primary care patients who had them did not appear to live shorter lives, and many of the causes blamed for night sweats turned out to be poorly supported. Menopause, anxiety, medicines, low blood sugar and alcohol cover most everyday cases.
What causes night sweats in women?
Menopause night sweats come from the brain's thermostat
In perimenopause the brain's thermostat misfires as estrogen swings and falls. Nerve cells that release neurokinin B become overactive, the comfortable temperature range narrows, and a small rise in core temperature is read as overheating. At night that sets off a hot flash in your sleep: a burst of heat, then heavy sweating that wakes you. That's why menopausal night sweats come in waves rather than lasting all night, and why many women also have hot flashes during the day.
Night sweats before a period and in pregnancy
Hormone shifts cause night sweats outside menopause too. Some women notice them in the days before a period, when estrogen drops, and in perimenopause this is often the first place hot flashes show up. Pregnancy is another common time: in the systematic review, the highest rate of night sweats, 60%, was among women on an obstetrics unit. Night sweats in pregnancy are usually harmless, but mention them to your midwife or doctor if you also have a fever.
Medicines that cause night sweats
Some antidepressants, steroids and painkillers change how the body controls sweating, and the NHS lists them among the most common causes of night sweats. If sweats started after a new prescription or a dose change, the medicine is a likely suspect. A doctor may switch you to a different one. The review also found that alpha blockers may reduce night sweats in people taking serotonin reuptake inhibitors, the most common type of antidepressant.
Anxiety, low blood sugar and alcohol
Anxiety can wake you soaked, often with a racing mind or a jolt of fear. Low blood sugar, which mostly affects people on diabetes medicine or after a skipped meal, and alcohol or drug use both trigger a stress response that brings on sweating. Cold sweats, clammy rather than hot, fit this group better than a menopausal hot flash does. These causes are common, and they often overlap with perimenopause.
Infections and other illness
Infection is a less typical cause and usually brings other signs: a very high temperature, feeling hot, cold or shivery, a cough or diarrhea, or weight loss you can't explain. Night sweats are linked with some cancers, autoimmune diseases and infections, but in primary care most people who report night sweats have none of these. That's why doctors look at the whole picture rather than the sweats alone.
Hyperhidrosis and unexplained night sweats
Hyperhidrosis is a harmless condition that makes you sweat too much all the time, day and night, not in sudden bursts with heat. And sometimes no cause of night sweats is found at all. The systematic review concluded that night sweats are a nonspecific symptom and that many questions about their causes remain unanswered, which is reassuring if your check-up comes back normal.
How common are night sweats?
From the studies on this page
of people report night sweats, depending on the group studied, from older primary care patients to women on an obstetrics unit
10–60%
Reported range across studies or subgroups
of women get hot flashes, night sweats or both during the menopause transition
50–75%
Reported range across studies or subgroups
median total duration of frequent hot flashes or night sweats in SWAN, the largest US study of the transition
7.4 years
Bar scaled to a 12-year reference span
Studies define night sweats differently, so estimates vary widely. In women in their 40s and 50s, menopause is by far the most likely cause.
Causes of night sweats and how to tell them apart
Night sweats have a short list of usual causes. The pattern of the sweats, what else comes with them and what changed recently usually point to the right one.
Perimenopause
Check →Sweats come in bursts with a wave of heat, often with daytime hot flashes, changing periods, poor sleep or mood changes.
Test: Over 45, identified from symptoms alone. No blood test needed
A medicine
Check →Sweats started after a new antidepressant, steroid or painkiller, or after a dose change.
Test: Medicine review with a doctor or pharmacist
Anxiety
Check →Waking with a racing mind or a jolt of fear, and worry or tension during the day.
Test: Doctor's assessment or talk therapy
Low blood sugar
You take diabetes medicine, skipped a meal or drank in the evening. Sweats feel cold and clammy, with shakiness.
Test: Blood sugar check
Infection or other illness
Fever, shivering, cough, diarrhea, or weight loss you can't explain.
Test: Doctor's assessment and blood tests
Hyperhidrosis
You sweat heavily day and night, not in bursts, and it started long before midlife.
Test: Doctor's assessment
How to stop night sweats
HRT for menopause night sweats
Strong evidenceIf your night sweats are menopausal, estrogen is the first-line treatment and reduces hot flash and night sweat frequency by about 75%. Tablets and patches work equally well. NICE advises offering HRT for these symptoms, and The Menopause Society calls it the most effective treatment for women within 10 years of their final period.
Related guide →Non-hormonal pills for night sweats
Strong evidenceFezolinetant, SSRIs, SNRIs and gabapentin all reduce hot flashes and night sweats when HRT isn't suitable. SSRIs and SNRIs such as paroxetine and venlafaxine cut frequency by about 40–65%. Gabapentin is often taken at bedtime because it also makes you sleepy. NICE recommends fezolinetant for moderate to severe symptoms when HRT is unsuitable.
Related guide →CBT for night sweats and broken sleep
Strong evidenceNICE suggests menopause-specific CBT for night sweats and the sleep problems they cause, alongside HRT or instead of it. It doesn't stop the sweats but makes them less disruptive and helps you get back to sleep faster.
Related guide →Bedroom fixes for night sweats
First stepKeep the bedroom cool, use light bedding in layers you can throw off, wear light nightclothes, and keep a fan and a cold drink by the bed. Cutting back on alcohol, caffeine, spicy food and hot drinks in the evening removes common triggers. These make nights more comfortable, but they haven't been shown to reduce how often menopausal sweats happen.
If a medicine causes night sweats
If this is the causeA doctor may switch you to a different medicine or change the dose. Don't stop a prescribed medicine on your own, especially an antidepressant or steroid, as stopping suddenly can cause other problems. For sweating on serotonin reuptake inhibitors, the review found alpha blockers may help.
Related guide →Treat anxiety or blood sugar causes
If this is the causeIf anxiety is behind the sweats, talk therapy such as CBT helps. If you're on diabetes medicine and wake sweaty and shaky, check your blood sugar and ask your doctor to review your dose. If alcohol is the trigger, cutting back in the evening usually stops the sweats quickly.
When night sweats need a doctor
Night sweats that wake you regularly or worry you
See a doctor. Most causes are harmless, but regular night sweats are worth a check, and the doctor will want to know about your other symptoms and medicines.
Night sweats with a fever, shivers, cough or diarrhea
See a doctor. This points to an infection rather than menopause.
Night sweats with weight loss you can't explain
See a doctor soon. Unexplained weight loss needs checking whatever the cause of the sweats.
Video: Why you wake at 3 a.m.: perimenopause and sleep
Read the transcript (716 words)▾
3:07. Again. Wide awake, soaked, and my brain is already writing tomorrow's to-do list.
If you wake in the small hours during perimenopause, you're in very large company. Here's why it happens, and what actually helps you sleep again.
In SWAN, three thousand and forty-five women aged forty-two to fifty-two were followed for seven years. As they moved through the transition, trouble falling asleep and staying asleep became more common. Early morning waking, by contrast, eased after menopause. So for many women, sleep gets harder, not easier, as the transition goes on.
There are three main reasons. First, night sweats. In SWAN, more frequent hot flashes meant higher odds of every kind of sleep trouble. Second, the hormones themselves. Falling estradiol was linked with more trouble falling and staying asleep, and rising FSH with more trouble staying asleep. Third, mood and worry. Anxiety and low mood keep the mind running.
Then something else happens. After weeks of waking, the brain can learn to wake at the same time even without a flash, and worrying about sleep keeps you awake longer. That's why insomnia can outlast the night sweats that started it.
Adults need seven to nine hours on average. Trouble sleeping that lasts three months or longer counts as long-term insomnia, and it deserves a plan of its own, not just a better pillow.
The approach with the strongest evidence is cognitive behavioral therapy for insomnia, or CBT-I. It uses sleep restriction, stimulus control and work on the thoughts that keep you awake. In a trial of women with hot flashes, six phone sessions cut insomnia scores about twice as much as education alone, and six months later eighty-four percent were in the no-insomnia range, compared with forty-three percent. UK guidelines suggest menopause-specific CBT for sleep problems linked to hot flashes.
When night sweats are what wakes you, hormone therapy reduces hot flashes by about seventy-five percent, and in SWAN, women using hormones after menopause reported less disturbed sleep.
Habits matter too. Go to bed only when you're sleepy. Get up at the same time every day, even after a bad night. Give yourself an hour to wind down. Keep the bedroom dark, quiet and cool. Exercise during the day, but not in the four hours before bed, and cut back on alcohol, caffeine and smoking.
Sleeping pills are rarely prescribed now, and only for a few days or weeks. Pharmacy sleep aids may help for one to two weeks at most.
Progesterone has a calming effect, and one review suggests bedtime micronized progesterone may help sleep and hot flashes in perimenopause. The trial evidence is limited, so it's one to discuss with a menopause-aware doctor rather than a proven fix.
Here's what to do at 3:07. CBT-I keeps the bed for sleep. If you've been lying awake for a while, you get up, do something calm in dim light, and go back only when you feel sleepy. Clock-watching makes it worse, so turn the clock away. And the next morning, you still get up at your usual time. It feels backwards, but it rebuilds the pressure to sleep the next night.
Keep a simple sleep diary for two weeks: when you went to bed, when you woke, whether a night sweat woke you. It shows you, and your doctor, what's driving the nights.
Sometimes poor sleep has another cause. Snoring, gasping or choking at night, with sleepiness in the day, needs checking for sleep apnea, often with a sleep study. Racing thoughts at bedtime or waking early with low mood can point to anxiety or depression. An urge to move your legs in the evening can be restless legs, and a blood test for low iron can help. A doctor can sort these out.
Sleep sits underneath a lot of other symptoms. In a 2023 survey of women aged forty to sixty, insomnia and fatigue topped the list of menopause symptoms. Poor sleep makes brain fog and fatigue worse, and when sleep improves, they often lift. In SWAN, the memory dip of perimenopause recovered after menopause. Fixing sleep is often the fastest way to feel like yourself again.
3:07 still happens sometimes. It just doesn't own the night anymore.
Find your stage in two minutes at perimenostage.com, and take your sleep diary to your doctor.
Every number in this video is sourced in the YouTube description.
Night sweats: questions women ask
What causes night sweats in women?
Menopause is the most common reason in midlife. Anxiety, some medicines such as antidepressants, steroids and painkillers, low blood sugar, alcohol and a harmless condition called hyperhidrosis are the other usual causes. Pregnancy and the days before a period can bring them on too. Infection is less common and usually comes with a fever.
Are night sweats a sign of cancer?
Rarely on their own. A systematic review found night sweats are common and nonspecific, and primary care patients who reported them did not appear to live shorter lives. See a doctor if they come with weight loss you can't explain, a fever or a cough.
Can perimenopause cause night sweats before periods stop?
Yes. Hot flashes and night sweats often start while periods are still coming, sometimes while they are still regular. In SWAN, women whose symptoms started early in the transition had them the longest, a median of more than 11.8 years in total.
Why do I wake up drenched but not hot?
The hot flash can peak and pass before you fully wake, leaving only the sweat. As it evaporates you can feel cold and shivery. Clammy, cold sweats with shakiness can also point to low blood sugar, especially if you take diabetes medicine.
How do I stop night sweats?
Treat the cause. For menopausal night sweats, the most effective option is HRT, which cuts frequency by about 75%; fezolinetant, SSRIs, SNRIs, gabapentin and CBT are alternatives. A cool bedroom and light layers make nights easier. If a medicine is behind them, ask your doctor about switching.
Why do I get night sweats before my period?
Estrogen drops in the days before a period, and in some women that is enough to trigger night sweats. In your 40s it's often an early sign of perimenopause, because hot flashes tend to appear around periods first. Our page on hot flashes before and during your period explains the pattern.
Related →Are night sweats normal in pregnancy?
They're common. In the systematic review, 60% of women on an obstetrics unit reported night sweats, the highest rate of any group studied. Hormone changes and a higher metabolism are the usual reasons. Tell your midwife or doctor if you also have a fever or feel unwell.
What's the difference between cold sweats and night sweats?
Night sweats soak your nightclothes and bedding, and in menopause they come with a wave of heat. Cold sweats feel clammy without the heat and usually come from a stress response, for example low blood sugar, anxiety or alcohol. Cold sweats with chest pain or breathlessness need emergency help.
Sources
- NHS. Night sweats.
- Mold JW, Holtzclaw BJ, McCarthy L. Night sweats: a systematic review of the literature. J Am Board Fam Med. 2012;25(6):878-93.
- Conklin M, Santoro N. Neurokinin receptor antagonists as potential non-hormonal treatments for vasomotor symptoms of menopause. Ther Adv Reprod Health. 2023;17:26334941231177611.
- NHS. Symptoms of menopause and perimenopause.
- Crandall CJ, Mehta JM, Manson JE. Management of Menopausal Symptoms: A Review. JAMA. 2023;329(5):405-420.
- Avis NE, Crawford SL, Greendale G, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015;175(4):531-9.
- NICE. Menopause: identification and management (NG23). Updated 2024.
- The North American Menopause Society. The 2023 nonhormone therapy position statement of The North American Menopause Society. Menopause. 2023;30(6):573-590.
- NHS. Things you can do to help menopause and perimenopause symptoms.
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